Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain.

نویسنده

  • M EBE
چکیده

Hayashi1) reported that a convulsive seizure can be induced on dogs, by injecting a very minute amount of sodium salt of glutamic acid into the cortex of the brain. We also observed a similar phenomenon caused by injecting the drug into the brain or the spinal cord of a frog or a toad. The present experiment was undertaken in order to investigate the effect of glutamic acid upon the potentials of the isolated toad's brain. The effects of NaCN and monoiodoacetic acid were also studied in comparison with that of glutamic acids

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

INVESTIGATION ON ANTI-GLUTAMIC ACID DECARBOXYLASE ANTIBODIES IN TYPE I DIABE TES MELLITUS

Antibodies directed against the enzyme glutamic acid decarboxylase (GAD) are believed to be the main cause of destruction of pancreatic islet cells in type I (insulin dependent) diabetes mellitus. The enzyme was found both in the brain and pancreatic beta cells. Although similarities in identity of GAD in human and rat brain have been demonstrated, little is known about the interaction betw...

متن کامل

Comparison Studies on Complexation of Molybdenum(VI) with Aspartic Acid And Glutamic Acid in Different Dielectric Constants1

Equilibria of the reaction of molybdenum(VI) with L-aspartic acid (Asp) and L- Glutamic acid(Glu) have been studied by spectrophotometric measurements in mixed solvent systems at an ionicstrength of 0.2 mol/dm3 sodium perchlorate, employed (15, 20, 25, 30± 0.1°C) at pH ranges of 3.2to 5.5 with a high ratio of ligand to metal. The stability constants of the complexes and theresulting free energy...

متن کامل

Significant Changes in the Activity of L-Glutamic Acid Decarboxylase of Mouse Hypothalamus After Peripheral Injection of Cholecystokinin-8 and Caerulein

The activity of one of the metabolizing enzymes of - aminobutyric acid, (GABA), was determined in mouse hypothalamus after peripheral injections of cholecystokinin-8 (CCK-8) and caerulein (CLN). The activity of this rate-limiting enzyme, L-glutamic acid decarboxylase, (GAD), did not change thirty minutes after peripheral injections of either CCK-8 or CLN in doses of 50g/kg body weight. Howeve...

متن کامل

P5: Evaluating The Toxicity of L-glutamic Acid on Brain via Histological and Locomotion Measures in Mice

لطفاً به چکیده انگلیسی مراجعه شود.

متن کامل

Evaluation of Neurogenic Potential of Human Umbilical Cord Mesenchymal Cells a Time- and Concentration- Dependent Manner

Background: Retinoic acid as one of the most important regulators for cell differentiation was examined in this study for differentiation of human umbilical mesenchymal cells (hUCM). Methods: After isolation, hUCM were evaluated for mesenchymal stem cell properties by flow cytometry and alkaline phosphatase assay. Also, doubling time of the cells and their differentiation potential into adipoge...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • The Tohoku journal of experimental medicine

دوره 56 1-2  شماره 

صفحات  -

تاریخ انتشار 1952